In Slay the Spire, relics are very effective against your enemies. Unlike potions, they do not lose their effect after use. There are many relics in the game. You can get them in different ways: get them from elite opponents as they drop a random relic and you can also buy them from the dealer. But you need gold for that. Therefore, we recommend you to kill as many elite opponents as possible.

Anchor (Each fight starts with 10 blocks) - An ordinary / common relic, which can be found in a normal run.

Ancient Tea Set (After a visit to the campfire you start a fight with 2 more energy). This is an ordinary / common relic and can be found in a normal run.

Art of War (If you do not play attacks during a turn, you will gain 1 energy next turn). An ordinary  / common relic, can be found in a normal run

Astrolabe (Once you get this relic, you can once select and transform 3 cards. After that they will be upgraded). This you’ll get after a boss fight.

Bag of Marbles (At the start of each fight 1x applies Vulnerable to all opponents). This is an ordinary  / common relic and can be found in a normal run

Bag of Preparation (At the start of each fight you draw two more cards). This is an ordinary / common  relic, can be found in a normal run.

Bird Faced Urn (Whenever you play a Power, you always heal 2 HP). This rare relic can be found during a normal run.

Black Blood (Replaces Burning Blood and heals for 10 HP at the end of the fight). Drop at Boss fight.

Slay the Spire, Relics Guide, Location

Black Star (Defeat an elite opponent and drop those 2 relics). Drop at Boss fight.

Blood Vial (To start a fight, you heal 2 HP). This is an ordinary / common relic and can be found in a normal run.

Bloody Idol (Whenever you receive gold, you will receive 2 HP at the same time). Random drop at events.

Blue Candle (Cursed cards can be played with it. Curse cards reduce your HP by 1 and disappear after use). This is an unusual / uncommon relic, can be found during a normal run.

Bottled Flame (Once you get this relic, you can choose an Attack card that is in your hand each time you start fighting). This is an unusual / uncommon relic, can be found during a normal run.

Bottled Lightning (Once you get this relic, you can choose a skill card that's in your hand every time you start fighting). This is an unusual  / uncommon relic, can be found during a normal run.

Bronze Scales (Whenever you take damage, you deal 3 damage). This is an ordinary / common relic, can be found in a normal run.

Burning Blood (At the end of a fight, you heal 6 HP). This is available from the beginning.

Calipers (At the beginning of each round, you lose only 15 blocks). This is a rare relic, can be found during a normal run.

Calling Bell (You will receive 3x curse and 3 relics). Drop at Boss fight

Cauldron (Once you get this relic, you can brew 5 random potions). This can be found at the dealer

Centennial puzzle (As soon as you take damage for the first time in the turn, you can draw 3 cards). This is an unusual / uncommon relic, can be found during a normal run.

Champion Belt (Whenever you use 1 Vulnerable, 1 Weak is added). This is a rare relic, can be found during a normal run.

Charon's Ashes (Whenever you use a card, you deal 3 damage to all enemies). This is a rare relic, can be found during a normal run.

Slay the Spire, Random Relic, Relics Guide, Location

Cursed Key (You gain 1 Energy at the beginning of each turn. Whenever you open a box, you get a curse). Drop at Boss fight.

Dead Branch (Whenever you use a card, you get a random card on your hand). This is a rare relic, can be found during a normal run.

Discerning Monocle (All dealer prices are reduced by 20 percent). This is an unusual / uncommon relic, can be found during a normal run.

Dream Catcher (Whenever you rest, you can add a card to your deck). This is an ordinary / common relic, can be found in a normal run.

Du-Vu Doll (For each curse in your deck, you start the battle with 1 additional strength). This is a rare relic, can be found during a normal run.

Ectoplasm (You get 1 energy at the beginning of each round, but you can not get any gold anymore). Drop at Boss fight

Enchiridion (Start each round with a random power card that costs you 0 Energy). This is a random drop at events

Eternal Feather (You heal 2 HP for every 5th card in your deck when you're at the campfire). Drop at Boss fight

Frozen egg (Once you receive this relic, you can select and improve a power). This is an ordinary  / common relic, can be found in a normal run.

Gambling Chip (Discard a number of cards at the start of each fight. Pull exactly as many). This is a rare relic, can be found during a normal run.

Ginger (You won't be weakened anymore) This rare relic, can be found during a normal run.

Girya (You can now receive strength from campfires (maximum 3)). This is a rare relic, can be found during a normal run.

Golden idol (Enemies lose 25 percent more gold). This is a random drop at events.

Gremlin Horn (Whenever an enemy dies, you can draw a card and gain 1 Energy). This is an unusual / uncommon relic, can be found during a normal run.

Happy Flower (You will receive 1 energy every 3rd round) This is an ordinary / common relic, can be found in a normal run.

Ice cream (Your energy preserves your energy between rounds). This is a rare relic, can be found during a normal run.

Juzu Bracelet (You no longer meet opponents in rooms that come with? Marked). This is an ordinary  / common relic, can be found in a normal run.

Kunai (Each time you play 3 Attack cards in a turn, you get 1 Skill). This is an unusual / uncommon relic, can be found during a normal run.

Lantern (You gain 1 Energy on the first round of each fight). This is an ordinary / common relic, can be found in a normal run.

Lee's Waffle (Your maximum HP will increase by 7 HP. In addition, you heal all your HP). This can be found at the dealer.

Letter Opener (Each time you play 3 skill cards in a turn, you deal 5 damage to all enemies). Unusual  / uncommon relic, can be found during a normal run.

Lizard Tail (If you take hits that would kill you, you will not die but heal for 50 percent of your maximum HP instead. Works only once). Drop at Boss fight.

Magic flower (Healing is 50 percent more effective during the fight). This is a rare relic, can be found during a normal run.

Mango (Your maximum HP will be increased by 14). This is a rare relic, can be found during a normal run.

Mark of Pain (You receive 1 energy at the start of each round. At the end of the fight, you add 2 wounds to your pile of shots). Drop at Boss fight.

Matryoshka (The next two boxes contain 2 relics. Boxes excluded from boss battles). This is an unusual / uncommon relic, can be found during a normal run.

Meat on the bone (If you finish a fight with less than 50 percent HP, you heal 9 HP). This is an unusual / uncommon relic, can be found during a normal run.

Medical Kit (You can now play status cards. They are consumed after application). This can be found at the dealer.

Membership Card (In future levels, traders will appear 50 percent more frequently. In addition, you will receive a 20 percent discount on all products). Can be found at the dealer.

Mercury Hourglass (At the start of your turn, you deal 3 damage to all enemies). This is an unusual / uncommon relic, can be found during a normal run.

Molten Egg (Once you receive this relic, you can select and upgrade an Attack card). This is an ordinary / common relic, can be found in a normal run.

Mummified hand (Whenever you play a power card, a random card in your hand costs 0 Energy for that turn). This is an unusual relic, can be found during a normal run.

Necronomicon (The first Attacl card you play in a round and cost 2 or more Energy is played twice. If you take this relic, you will be cursed). Random drop at events.

Nilry's Codex (At the end of each round, you can choose 1 - 3 random cards to mix in your pick pile). Random drop at events

Ninja scroll (You start every fight with 3 Shiv cards in your hand). This is an unusual / uncommon relic, can be found during a normal run

Nloth's poison (Triples the chance to get rare cards as monster rewards). Random drop at events

Odd Mushroom (If you have Vulnerable status, you only suffer 25% more damage than 50%). Random drop at events

Oddly Smooth Stone (At the beginning of each fight you get 1 skill). This is an ordinary / common relic, can be found in a normal run

Old Coin (You will receive 250 gold once). This is a rare / uncommon relic, can be found during a normal run.

Omamori (Save the next 2 curses you receive). This ia an ordinary / common relic, can be found in a normal run.

Orichalchum (When you finish your round with a Block card, you get 6 blocks). This is an ordinary  / common relic, can be found in a normal run.

Ornamental fan (Each time you play 3 Attack cards in a turn, you get 4 blocks). An unusual / uncommon relic, can be found during a normal run.

Orrery (Select 5 cards and add them to your deck). This is an Unusual / Uncommon relic, can be found during a normal run.

Pandora's box (All strikes and defenses are changed). Drop at Boss fight.

Pantograph (At the start of a boss fight, you heal 25 HP). This is an unusual / uncommon relic, can be found during a normal run.

Paper Kranes (Enemies with weakness suffer 50 percent more damage than 25 percent). This is an unusual / uncommon relic, can be found during a normal run.

Paper Phrog (Wounded enemies suffer 75 percent more damage than 50 percent). This is an unusual / uncommon relic, can be found during a normal run.

Peace Pipe (You can now remove cards from your stack when you are on camp fire). This is a rare relic, can be found during a normal run.

Pear (Your maximum HP will be increased by 10). This is an uncommon / unusual relic, can be found during a normal run.

Pen Nib (Every 10th attack from you has double damage). This is an ordinary / common relic, can be found in a normal run.

Philosopher's Stone (You get 1 energy every round. When starting a fight, each fighter gets 2 strength). Drop at Boss fight

Prayer wheel (Chests that are not from bosses now have cards) This is an ordinary / common relic, can be found in a normal run.

Question Card (For card rewards, you can now choose from 4 instead of 3 cards). Drop at Boss fight.

Red Mask (At the beginning of the fight, you apply 1 weakness to each opponent). This is a random drop at events

Red skull (If your health drops below 50 percent, you have 3 additional strength points). This is a rare relic, can be found during a normal run.

Regal Pillow (If you rest, you will also heal 15 HP). This is an ordinary / common relic, can be found in a normal run.

Ring of the Snake (At the start of each fight, you can draw 2 extra cards). Available since the beginning.

Runic Cube (Your maximum HP will be reduced by 20 percent. Whenever you lose HP, you draw a card). Drop at Boss fight

Runic Dodecahedron (When your HP is full, you gain 1 Energy at the beginning of each turn). This is an unusual / uncommon relic, can be found during a normal run.

Runic Dome (You get 1 energy to start each round. But you no longer see the intentions of the opponents over their heads). Drop at Boss fight

Runic Pyramid (At the end of each turn, you do not discard cards from your hand and draw one card less each turn). Drop at Boss fight

Self forming clay (Whenever you lose HP in combat, you get 3 blocks on the next turn). This is an unusual / uncommon relic, can be found during a normal run.

Shovel (You can now dig for loot at campfires). This is a rare relic, can be found during a normal run.

Shuriken (Whenever you use 3 Attack cards in a turn, you gain 1 Strength). This is an unusual / uncommon relic, can be found during a normal run.

Singing Bowl (Whenever you skip a card reward, your maximum HP will increase by 2). This is an ordinary / common relic, can be found in a normal run.

Smiling Mask (If you remove a card from the dealer, the service costs only 50 gold (always). This is an unusual / uncommon relic, can be found during a normal run.

Snecko Eye (Draw 2 extra cards each turn. For this you start every fight with confusion). Drop at Boss fight.

Snecko Skull (Whenever you use poison, 1 poison is added). This is an ordinary / common relic, can be found in a normal run.

Sozu (Receive 1 Energy at the beginning of a turn. But you can not use potions anymore). Drop at Boss fight

Spirit poop (Removes an inappropriate card). Random drop at events.

Strange Spoon (Cards that are consumed after use are discarded 50 percent of the time instead of this effect). can be found at the dealer.

Strawberry (Increases your maximum health by 7 HP). This is an ordinary / common relic, can be found in a normal run.

Sundial (Every 3rd time you mix your deck, you gain 3 energy). This is a rare relic, can be found during a normal run.

The Courier (The dealer will no longer be sold out and will always sell you cards, relics and potions. This is an unusual / uncommon relic, can be found during a normal run.

The Specimen (Whenever an opponent dies, all the poison that he had applied to a random opponent). Drop at Boss fight.

Thread and needle (At the start of a fight, you will receive 5 Metal-Coated Armor). This is a rare relic, can be found during a normal run.

Tingsha (Whenever you discard a card during your turn, you deal 3 damage. This one goes to a random opponent. Applicable per card. (This is a rare relic, can be found during a normal run.

Tiny Chest (You will receive 30 gold once. In addition, increases your chance to find 10 percent more treasures in). This is an ordinary / common relic, can be found in a normal run.

Tiny House (You will receive a potion, 30 gold and a card. In addition, your maximum health increases by 5 HP). Drop at Boss fight.

Toolbox (At the start of a fight, you add any colorless card to your hand). This is an unusual / uncommon relic, can be found during a normal run.

Torii (Whenever you have to take 5 unblocked Attack damage, it reduces to 1). This is a rare relic, can be found during a normal run.

Tough bandages (For every discarded card in a turn you get 3 blocks). This is an unusual / uncommon relic, can be found during a normal run.

Toxic Egg (Once you pick up this relic, pick a skill card and upgrade it). This is an ordinary / common relic, can be found in a normal run.

Toy ornithopter (Each time you heal with a potion, you heal 3 HP). This can be found at the dealer

Unceasing Top (If you have no cards in your hand, you may draw one). This is a rare relic, can be found during a normal run.

Vajra (You gain 1 Strength at the beginning of each fight). This is an ordinary / common relic, can be found in a normal run.

Velvet Choker (Each turn you gain 1 Energy, but you can not play more than 6 cards per turn). Drop at Boss fight.

Whetstone (Once you pick up this relic, you can upgrade two random Attack cards). This is an ordinary / common relic, can be found in a normal run.

White Beast statue (Potions are always dropped after a fight). Drop at Boss fight

All the tasks can be found below:

- Bloody Idol: Give the Golden Idol to Deity to lose the effect.

- Enchiridion, Necronomicon and Nilry's Codex: Ask for a book in the event with the Cursed Book as one of the three possible outlets.

- Nloth's Gift: Give Nloth one of the two random relics in his event.

- Odd Mushroom: Hit the ground and kill all the enemies in the Mushroom event.

- Red Mask: Give all your gold in the Mask Event.

- Spirit Poop: Burn a curse in the Spirit Fire event.

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