All New Bosses in Genshin Impact Luna IV (Version 6.3) & How to Defeat Them — The Ultimate Expert Guide

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Genshin Impact’s Luna IV update (Version 6.3) brings one of the most anticipated content waves of the year — including five major new bosses hidden throughout the expanded Nod‑Krai region, a dramatic weekly challenge, and powerful foes tied to the main story. Whether you’re hunting Hexadecatonic Mandragora in the wild or gearing up for the harrowing weekly fight against The Doctor, this guide breaks down every boss’s mechanics, weaknesses, and the best strategies to beat them.

🗺️ New Bosses Added in Luna IV

Version 6.3 adds a mix of Local Legend bosses, elite world enemies, and a new weekly boss that’s unlocked after progressing through the Archon quest:

🐍 Hexadecatonic Mandragora

  • Type: Local Legend

  • Location: Southwest of Dreadshade Mire

  • Summary: A giant mushroom‑like boss that switches between phases with distinct attack patterns.

🐺 Hiljetta

  • Type: Local Legend

  • Location: Wavechaser Plain

  • Summary: A slow but devastating foe whose every attack can deal massive damage.

🐕 The Homesick Lone Wolf

  • Type: Local Legend

  • Location: South of Kipumaki Cliff

  • Summary: Summons ancestors with shields that must be broken before you can safely deal damage.

🧪 Heretic of the False Moon — The Doctor

  • Type: Weekly Boss

  • Location: False Moon Institute Domain (Unlocked after Archon Quest)

  • Summary: A narrative centerpiece boss with unique combat rules and battle‑stage transformation phases.

All New Bosses in Genshin Impact Luna IV (Version 6.3) & How to Defeat Them — Guide

👁️ Lord of the Hidden Depths — Whisperer of Nightmares

  • Type: Elite World Boss

  • Location: Ashveil Peak / Shadowed Hollow area

  • Summary: A fearsome being tied to the wilds of Nod‑Krai, able to summon minions and shield itself.

🧠 How to Defeat Each New Boss

Below are practical, battle‑tested tips and counter strategies that address each boss’s mechanics.

⚔️ Hexadecatonic Mandragora — Pyro Reactions Win Fast

This mushroom boss shifts between:

  • A large, hardy primary form

  • A cluster of smaller spore‑like entities in Phase 2

Strategy Tips:

  • Use Pyro characters to trigger strong reactions against its Dendro attacks. Pyro reactions like Overloaded and Burning significantly reduce its health and shorten phases.

  • Focus fire on smaller mushrooms quickly during Phase 2 to prevent them overwhelming your team.

  • Stay mobile to avoid area jumps and projectile volleys.

Recommended Teams: Hu Tao, Xiangling, Klee, Bennett for Pyro pressure + healing.

🌀 Hiljetta — Master Avoidance & Freeze

Hiljetta may look slow, but every strike hits hard.

Key Weakness: Weak to Freeze reactions.
Winning Tips:

  • Bring a Cryo + Hydro combo to trigger Freeze repeatedly and prevent it from using armored attacks.

  • Watch long wind‑ups — side‑step early rather than dodge at the last second.

  • If Freeze teams aren’t available, use high‑burst DPS and shields to tank hits and rotate safely.

Recommended Teams: Layla + Barbara + Cryo + Hydro support.

🐺 The Homesick Lone Wolf — Break the Armor

Unlike the other local legends, this boss brings shielded ancestors into battle that must be broken quickly.

Best Approach:

  • Use Electro or Pyro Swirl reactions to destroy shields efficiently.

  • Once shields drop, unleash your highest DPS to capitalize on the brief vulnerability window.

  • Avoid clustering when it summons its ancestors — AoE cleans up faster.

🩸 Heretic of the False Moon — The Doctor (Weekly Boss)

This is the most mechanically intense fight in Luna IV — and one with some of the best rewards.

What to Know Before You Fight:

  • You unlock The Doctor as a weekly boss by completing the Nod‑Krai Archon Quest.

Core Mechanics:

  • Moonfall Impact: Huge AoE attack that hits hard; avoid it by hiding behind terrain or moving out of telegraphed zones.

  • Moonwither Realm: Changes the battlefield mid‑fight, forcing you to adapt positioning and rotation.

Pro Tips:

  • Bring shield characters like Zhongli or healer support like Barbara/Bennett to manage sustained damage.

  • Rotate characters to exploit openings between large attacks.

  • Patience and pattern recognition are key — he learns and punishes aggressive damage spamming.

Rewards:
Defeating The Doctor yields ascension materials and talent books required for mid‑to‑high‑tier characters, making him indispensable for grind progression.

👁️ Lord of the Hidden Depths — Whisperer of Nightmares

This elite boss resides within the Shadowed Hollow, an ominous new area in Nod‑Krai.

Combat Style:

  • Can summon minions to assist it.

  • Builds shields that prevent direct damage.

Best Counters:

  • Focus on Lunar reactions (a mechanic emphasized in the Luna IV patch) to overcome its defenses.

  • AoE damage helps clear minions fast so you can return attention to the boss.

Recommended Team Elements:
Geo + Hydro + Electro + Pyro to maximize reaction throughput and flexibility.

💡 General Strategies for Luna IV Boss Fights

Here are universal tips that apply across all bosses to help you keep fights clean and efficient:

🪄 Prioritize Elemental Reactions

Elemental reactions are critical in Luna IV because bosses have high resistance to basic attacks and gradually open windows for reaction damage. Freeze, Overloaded, Electrocharged, and Lunar reactions all have situational use depending on boss.

⚙️ Rotation Is Key

Quick character swapping helps manage:

  • Shields

  • Burst windows

  • Energy cycles

  • Defensive cooldowns

🛡 Boost Survivability

  • Shields (Zhongli, Noelle) and heals (Bennett, Barbara) drastically reduce wipe chances.

  • Avoid cornering yourself near hazards; bosses like The Doctor manipulate the battlefield.

🧠 Why These Bosses are Worth Learning

The Luna IV bosses not only expand the Nod‑Krai narrative arc but also form core parts of mid‑to‑endgame progression. Weekly bosses like The Doctor drop ascension and talent materials you can't farm elsewhere, giving value beyond just storyline satisfaction.

Defeating local legend bosses unlocks challenges and achievements, which often reward Primogems, Mora, and other valuable resources — making strategic play more rewarding than simple brute force.

🧩 Pro Tips From the Community

Here are some player‑verified tips that help in real runs:

  • Watch patterns first: Many bosses telegraph their biggest hits well in advance — learn the cues and dodge early. (Community consensus)

  • Don’t rush burst rotations: Charge when safe, and use defensive cooldowns strategically. (Experienced player advice)

  • Use summons and crowd control: Helps in fights like Whisperer of Nightmares that spawn adds.

🏁 Final Thoughts

Genshin Impact’s Luna IV bosses push the boundaries of combat in Version 6.3 — from strategic elemental counters against Mandragora and Hiljetta to the disciplined endurance fight against The Doctor. These encounters reward mastery and patience, and knowing the mechanics ahead of time gives you a huge competitive edge.

Have you faced all five bosses yet? Share your strategies or team comps in the comments — or bookmark this guide for your next adventure in Nod‑Krai!

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