Unlock every trophy and achievement in Resident Evil Requiem with this complete guide — including safe codes, collectible checklists, combat strategies, difficulty tips, and clear playthrough roadmaps across platforms (Switch 2, PS5/PS5 Pro, PC, and Xbox). Whether you’re a newbie or a completionist, this guide will help you reach 100 % with as few playthroughs as possible.
Trophy & Achievement Categories
Trophies and achievements in Requiem are grouped by type:
Story & Progression – Earned as you advance the narrative.
Difficulty Challenges – Complete missions on Casual, Standard, Classic, and Insanity to unlock these.
Combat & Skill – Special kill methods and combat feats.
Collectibles & Exploration – Files, safes, Mr. Raccoons, BSAA Containers, Plants, and Coins.
Timed & Challenge Runs – Speedruns or minimalist runs for advanced players.
Platform Platinum / Master – Unlock everything for the top tier.
This guide tells you what to unlock and how to unlock it efficiently.
Missable Trophies & Key Warnings
Before anything else:
🛑 Missable Trophy Warning:
Many collectibles (files, safes, Mr. Raccoons, BSAA containers, Plant 43 seedlings) are permanently missable if you progress past areas like the Care Center or enter ARK lower levels.
Always check that your progress is near 100 % before advancing. Manual save backups help avoid extra playthroughs.
Safe & Locker Codes
Opening all safes unlocks the No Safe Is Safe trophy and provides valuable gear. These codes are confirmed from reputable game guides:
| Location | Combination | Reward | Notes |
|---|---|---|---|
| Care Center: Admissions Safe | Left 9 → Right 15 → Left 7 | Handgun Sight / Muzzle Brake | Grace / Leon |
| West Wing: Staff Locker | C → A → R | Shotgun Shells / Handgun Ammo | Both |
| Pharmacy: Metal Wall Safe | 02 → 27 → 98 | High‑Grade Gunpowder | Grace only |
| Morgue Freezer | C → O → L → D | Hemolytic Injector Refill | Grace only |
| Resident Doctors’ Office | Right 6 → Left 2 → Right 11 | Inventory Expansion (Hip Pouch) | Both |
| R.P.D. Ruins: Waiting Room | Left 10 → Right 4 → Left 3 | Extended Mag | Leon only |
| R.P.D. Shower Locker | B → I → O | Flash Grenade | Leon only |
| ARK: Bio‑Storage Terminal | 8 → 5 → 1 → 2 | Requiem Ammo | Both |
| ARK: Security Office Safe | Left 25 → Right 10 → Left 31 | High‑Capacity Battery (Axe) | Leon only |
💡 Pro‑Tip: To earn No Safe Is Safe, open all safes in a single campaign cycle. Some safes are only accessible during specific character chapters — plan Grace and Leon runs accordingly.
Collectibles Checklist
Completing these collectibles contributes directly to important trophies and helps track your completion percentage:
| Collectible Type | Total | Trophy |
|---|---|---|
| Mr. Raccoon Memoriam | 25 | You Little Rascal! |
| In‑Game Files | 75 | Case Closed |
| BSAA Containers | 3 | Crate Expectations |
| Plant 43 Seedlings | 9 | Not Today, Buds! |
| Antique Coins | 19 | Used for upgrades / completion |
📌 Collectibles are often tucked away in hidden rooms and optional paths — use a checklist or the above table to mark them off before advancing the story.
Story & Progression Trophies
These unlock naturally as you play through the campaign:
| Trophy | Unlock |
|---|---|
| Deja Vu | Begin the Wrenwood outbreak |
| Descent Into Darkness | Enter Care Center basement |
| A Harsh Reality | Escape Care Center |
| The Hero Returns | Reach R.P.D. station |
| I Remember That, Too | Defeat Super Tyrant |
| Umbrella’s Legacy | Find ARK |
| Hope and Requiem | Finish main story |
These require no special conditions and can be collected on the first playthrough.
Difficulty & Challenge Trophies
To get all difficulty trophies, plan at least two fuller runs:
| Trophy | Requirement |
|---|---|
| Rookie Agent | Complete on Casual |
| Rising Agent | Complete on Standard (Modern) |
| Resolute Agent | Complete on Standard (Classic) |
| Remarkable Agent | Complete on Insanity |
Pro Tip:
Completing on Insanity automatically unlocks the lower difficulty trophies. Insanity restricts resources and changes enemy placements — practice routes and stockpile items beforehand.
Combat & Skill Trophies
Combat trophies require strategic plays:
Bang For Your Buck: Kill 3 enemies with one Requiem shot.
Cat Got Your Tongue?: Use the hatchet to slice off a Licker B2’s tongue.
Internal Dispute: Use enemy positioning to make them harm each other.
Order Up!: Defeat the chef enemy.
Deadly Duet: Defeat the two Singers.
Combat Pro Tips:
Group weaker enemies before using splash or high‑damage attacks for multi‑kill trophies.
For precision trophies, stagger strong enemies first and time parries or weapon swaps.
Playthrough Roadmap (Recommended Sequence)
Here’s an efficient path to 100 % completion:
🧪 Step 1 — Casual Run (Grace First)
Focus on story progression.
Gather easy collectibles and document missable collectibles.
🆚 Step 2 — Standard Run (Leon First)
Hunt collectibles missed on your first run.
Focus on combat trophies and lower difficulties.
💀 Step 3 — Insanity Run
Unlock the high‑difficulty trophies.
Maximize resource usage and plan routes carefully.
⏱ Step 4 — Speedrun/Challenge
Use the Infinite Weapon unlocks you’ve earned to go for Speed Demon, Minimalist, and Never Touch the Stuff achievements.
⚠️ ARK Alert: Once you ride the elevator to ARK’s lower levels, you cannot return to the Care Center or R.P.D. ruins — secure all safes and collectibles before progressing.
Platform‑Specific Tips
📺 PlayStation (PS5 / PS5 Pro)
PS5 shows trophy progress in the system menu; use manual saves right before difficult segments.
Platinum trophy unlocks by collecting all other trophies.
🎮 Xbox Series X/S & PC
Use achievement trackers on Xbox Live or Steam to monitor your percentages.
Steam allows custom screenshots of safe combos and collectibles for tracking.
🕹️ Nintendo Switch 2
Switch 2 has in‑game records and progress menus that help track collectibles even without a formal trophy system.
Battery life optimization (e.g., 30 FPS cap) may extend play sessions during long runs.
Related Guides (Must‑Read)
you might also find these optimization guides useful for performance and settings:
🔗 Resident Evil Requiem on Nintendo Switch 2: Performance Review vs PS5 Pro & PC
https://www.dtgre.com/2026/02/resident-evil-requiem-switch-2-vs-ps5-pc-performance.html
🔗 Resident Evil Requiem: Best Settings for Switch 2, PS5 Pro, PC & Xbox
https://www.dtgre.com/2026/02/resident-evil-requiem-best-settings-switch2-ps5-pc-xbox.html
These will help you get the smoothest frame rate, visuals, and control response as you pursue trophies.
FAQ
Q: Can I unlock all trophies in one playthrough?
A: No — some trophies require multiple playthroughs (Insanity, Combat challenges, Speed runs).
Q: Do difficulty trophies stack?
A: Yes — completing Insanity will unlock lower difficulty trophies.
Q: Are there missable trophies?
A: Yes — collectibles and safes won’t be reachable once you advance past certain story points.
Q: How many Mr. Raccoons are there?
A: 25 total, spread across Rhodes Hill and ARK areas.
Q: Is there infinite ammo unlock?
A: Yes — earned after completing specific challenges in prior playthroughs.
Final Tips for Completionists
Use save slots strategically before entering new areas.
Track your collectibles in a checklist to avoid replaying chapters.
Combine trophy requirements (e.g., combat challenges + difficulty runs).
Refer to safe code and collectible tables frequently during runs.
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