Duriel & Uber Boss Target Farming in Diablo 4 Season 9 – How to Farm Mythic Uniques Efficiently

Season 9: Sins of the Horadrim is here, and so is your best chance to get the most powerful loot in Diablo 4: Mythic Uniques. Whether you’re after Harlequin Crest, Doombringer, or class-specific god-rolls, targeted Uber Boss farming is the only consistent way to get them.

In this guide, we’ll walk you through how to farm Duriel, Andariel, Belial, and more for optimal drop rates, how Resplendent Sparks work, and the best strategies to maximize your time and gold.

🧬 What Are Mythic Uniques?

Mythic Uniques are Season 9’s highest-tier items, offering build-defining powers.
Only drop from Uber-level bosses in Torment I–IV or via Resplendent Spark crafting.
Drop chance is approximately 2% per kill on Torment IV—very low, but targetable.

🗺️ Bosses That Drop Mythic Uniques

🔥 Duriel, King of Maggots

Best Mythic drop rate of all bosses.
Requires 3 Shards of Agony + 3 Slime-Covered Incubators.
Great for farming Harlequin Crest, Doombringer, Tempest Roar, and more.

🕷️ Andariel, Maiden of Anguish

Drops mostly the same loot pool as Duriel.
Requires 3 Pincushioned Dolls + 3 Shards of Agony.
More Poison-based builds can benefit from her unique items.

🐍 Belial, Lord of Lies

Highest chance for Ancestral Uniques on chest open.
Mythic drop rate slightly below Duriel/Andariel.
Requires 3 Rotten Cores + 3 Abhorrent Hearts.

🐐 Harbinger of Hatred (Uber Lilith Variant)

Rarely farmed due to difficulty but drops all Mythics, especially The Grandfather and Melted Heart.

💎 How to Get Resplendent Sparks

Resplendent Sparks are used to craft Mythic Uniques at the Jeweler (targeted) or Blacksmith (random).

How to Earn Sparks:
- Salvaging duplicate Mythic Uniques = 1 Spark
- First kill of Tormented Boss = 1 Spark (once per account)
- Uber Lilith clear = 1 Spark
Crafting Costs:
- 🔸 2 Sparks
- 💰 50M Gold
- 💠 Various Runes (Farmed from Strongholds/Nightmares)

💡 Pro tip: If you loot a duplicate Mythic, don’t sell—salvage it to build toward the Mythic you actually want.

🔁 Best Farming Routine

Step	Action	Why It Works
1	Farm Duriel or Andariel	Best Mythic drop odds
2	Rotate with Belial runs	High-value Ancestral loot
3	Clear Nightmare Escalations	Chest rewards + XP + Sigils
4	Salvage duplicate Mythics	Build Sparks
5	Use Jeweler to target-craft	Avoid RNG with Sparks

⚙️ Required Summoning Materials

Boss	Materials Needed	Where to Farm
Duriel	3 Shards of Agony + 3 Slime-Covered Incubators	Varshan, Beast in Ice, Grigoire
Andariel	3 Shards of Agony + 3 Pincushioned Dolls	Lord Zir, Beast in Ice
Belial	3 Abhorrent Hearts + 3 Rotten Cores	Urivar, Andariel, Strongrooms

👥 Solo vs Group Runs

Solo Runs = slower clears, but more loot is yours.
4-Player Groups = faster boss kills + shared materials.
- Mythic drop chance per player is unchanged.
- Players can rotate summons for efficient farming.

💬 Community tip: Rotate boss summons in Discord groups to share entry costs and loot opportunities.

⚒️ Best Builds for Boss Farming

Class	Build Focus	Why It Works
Necromancer	Minion Overload + Arcana regen	Survive long fights, free DPS
Sorcerer	Hydra + Ophidian Spellcraft	Excellent single-target uptime
Spiritborn	Quill Volley + Catalyst spam	High poison DoT vs bosses
Barbarian	Hammer of the Ancients	Stun-lock potential vs elites
Rogue	Flurry + Cold Imbue	Consistent AoE and evade uptime

📦 Final Tips & Efficiency Boosters

Craft Elixirs before runs:
- Precision Elixir = +5% XP
- Mythic Find Elixirs = better loot odds (community tested)
Use Sigil Dust to reroll dungeons with higher density.
Always clear Escalating Nightmares when boss mats are low—XP + loot efficient.

📚 Community Resources & Tools

📝 Related Season 9 Articles

🏁 Conclusion

Season 9 offers the most efficient and rewarding way to target Mythic Uniques in Diablo 4 to date. By focusing your time on Duriel, Andariel, and Belial, salvaging duplicates, and crafting with Resplendent Sparks, you can reliably obtain best-in-slot gear without relying on pure RNG.

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